Description
Mestinon 60mg Tablets contain the active ingredient pyridostigmine bromide, a prescription medication that treats myasthenia gravis, a chronic autoimmune disorder causing muscle weakness and fatigue. As an orally active cholinesterase inhibitor, it works by slowing the breakdown of acetylcholine, a neurotransmitter essential for muscle contraction, thereby improving nerve impulse transmission at the neuromuscular junction and enhancing muscle strength. Pyridostigmine is also used for other off‑label indications such as paralytic ileus and post‑operative urinary retention. Each 60mg tablet allows for individualised dosing to maximise relief during periods of greatest weakness.
Key Features
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Active Ingredient: Contains pyridostigmine bromide 60mg, a well‑established cholinesterase inhibitor.
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Effective for Myasthenia Gravis: Specifically indicated for the symptomatic treatment of myasthenia gravis, a condition that causes muscles to weaken or fatigue easily.
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Proven Mechanism: Inhibits the destruction of acetylcholine, allowing freer transmission of nerve impulses across the neuromuscular junction to help strengthen muscles.
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Longer Duration: Offers a longer duration of action and fewer gastrointestinal side effects compared to older agents like neostigmine.
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Flexible Dosing: The 60mg strength allows for customised dosing (usually 5 to 10 tablets daily) to provide relief when maximum strength is needed.
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Prescription Only: A prescription-only medicine (POM) that must be used under the supervision of a healthcare provider.
Technical Data Table
| Attribute | Specification |
|---|---|
| Product Name | Mestinon 60mg Tablets |
| Active Ingredient | Pyridostigmine Bromide |
| Strength | 60mg per tablet |
| Formulation | Oral tablet (regular release) |
| Therapeutic Class | Cholinesterase inhibitor / Cholinergic muscle stimulant |
| Indications | Symptomatic treatment of myasthenia gravis. Off‑label: paralytic ileus, post‑operative urinary retention. |
| Mechanism of Action | Inhibits acetylcholinesterase, prolonging the action of acetylcholine at the neuromuscular junction to improve muscle contraction and strength. |
| Route of Administration | Oral |
| Dosage | Highly individualised. The average dose is 600mg (10 tablets) daily, divided into 5 or 6 smaller doses spaced throughout the day. The maximum dose can be up to 1500mg daily in severe cases. Adjust to times when maximum strength is needed. |
| Prescription Status | Prescription Only Medicine (POM) |
| Storage | Store at controlled room temperature, protected from light and moisture. |
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