Description
Metoclopramide 10mg Tablets are a prescription medicine used to treat symptoms of slow stomach emptying (gastroparesis) in diabetic patients. It works by increasing the movements or contractions of the stomach and intestines, helping to relieve nausea, vomiting, heartburn, a feeling of fullness after meals, and loss of appetite. It is also used to treat heartburn in patients with gastroesophageal reflux disease (GERD) who have not responded well to other treatments. As a dopamine D2 antagonist, it helps prevent nausea and vomiting in various conditions, including those induced by chemotherapy or radiotherapy, and it may also be used to relieve nausea associated with migraine.
Key Features
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Contains Metoclopramide Hydrochloride 10mg, a potent antiemetic and gastroprokinetic agent.
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Enhances gastrointestinal motility, helping to treat gastroparesis (delayed stomach emptying), especially in diabetic patients.
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Relieves a range of digestive symptoms, including nausea, vomiting, heartburn, post-meal fullness, and loss of appetite.
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Effective for GERD (gastroesophageal reflux disease) in patients who have not responded adequately to other therapies.
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Also used to prevent nausea and vomiting induced by chemotherapy, radiotherapy, or migraine.
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Works by blocking dopamine receptors and increasing acetylcholine release, thereby improving gastric emptying.
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Available in Kenya under brand names such as Metcos, Metomed, and Metoprix.
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Prescription Only Medicine (POM).
Technical Data Table
| Attribute | Specification |
|---|---|
| Product Name | Metoclopramide 10mg Tablets |
| Active Ingredient | Metoclopramide Hydrochloride |
| Strength | 10mg per tablet |
| Formulation | Oral tablet (disintegrating and standard) |
| Therapeutic Class | Antiemetic / Prokinetic Agent (Dopamine D2 antagonist) |
| Indications | Diabetic gastroparesis, GERD (refractory), prevention of chemotherapy/radiotherapy-induced nausea and vomiting, migraine-associated nausea |
| Mechanism of Action | Increases gastric motility and accelerates gastric emptying; also has central antiemetic effects by blocking dopamine receptors in the chemoreceptor trigger zone (CTZ) |
| Route of Administration | Oral |
| Dosage (Gastroparesis) | 10mg taken 4 times daily, 30 minutes before meals and at bedtime, for 2 to 8 weeks |
| Prescription Status | Prescription Only Medicine (POM) |
| Storage | Store in a cool, dry place below 25°C, protected from light and moisture |
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